1. anyhow
    • 何しろ話してごらん
    • At any rate [In any case/Anyhow/Anyway], tell me about it.
    • 何しろここは辺ぴな田舎ですからね
    • We are in an out-of-the-way place, you know.
    • あの男は扱いにくいよ,何しろ頑固だもの
    • He is very difficult to deal with ― he is so obstinate.