drive a person to despair=throw a person into despair
人を絶望に追い込む
drive a person to distraction
人をひどくいらいらさせる
drive [reduce] a person to the (utmost) extremity [extremities]
人を窮地に追い込む
drive a railway across the desert
砂漠に鉄道を敷く
drive [pull up] a stake
杭を打つ[抜く]
drive a tunnel through a hill
丘にトンネルを掘る
drive a wedge into [between] ...
…に[の間に]くさびを打ち込む
drive at 60 mph
時速60マイルで運転する
drive at a snail's pace
のろのろと運転する
drive at [with] a speed of 50 miles per [an] hour
時速50マイルで運転する