It's criminal to waste so much time.
そんなに多くの時間をむだにするなんてけしからん
It's curtains for me.
これで一巻の終わりだ
It's difficult to imagine Bob taking care of a baby.
ボブが赤ん坊の世話をしているところは想像しにくい
It's dogged as [that] does it.
((諺))がんばってこそ事は成る
It's down to him to support his family.
家族の扶養は彼の肩にかかっている
It's early days yet.
まだ始まったばかりだ
It's early yet.
まだ早い(◆否定文はIt isn't early any more.)
It's easy to be wise [Wise] after the event.
((英・諺))事の直後に対策に気づくのはたやすいこと;下衆の後知恵
It's even chances that ....
…かどうかは五分五分だ
It's evident that he's in love.
彼が恋をしているのは明らかだ