It is worthwhile to have a meeting.
会議をする価値がある
It is wrong of you to insult others.
人を侮辱するのはいけない
It is you who are [is] angry.
腹を立てているのは君のほうだ(◆areのほうが一般的)
It is yours to support her.
彼女を扶養するのはあなたの責任だ
It isn't as if I hadn't warned him.
彼に警告しなかったわけじゃないのに
It isn't cold; on the contrary it is hot.
それは冷たくないどころか熱い
It isn't just any day.
今日は特別な日だ
It isn't wise to go there direct.
直行するのは賢明ではない
It just isn't true.
それはまったく真実でない
It kills me to think of it.
それを考えただけで死にそうになる