It's no laughing matter.
笑い事ではない
It's no picnic.
楽な仕事[こと]じゃない
It's no use expecting support from them.
彼らに支持を求めてもむだだ
It's no use on earth.
それはちっとも役に立たない
It's no use!
((略式))(これ以上やっても)むだだ,だめだ
It's no wonder (that) you couldn't finish it.
((英))全部できなくても不思議はない
It's not all that hot.
それほど暑くない
It's not just another restaurant.
そこいらのレストランとは違う
It's not more than two miles to the airport.
空港までせいぜい2マイルだ
It's not my fault.
私が悪いんじゃない