with open [undisguised] contempt
明らかにさげすんで
with open [outright] hostility
あからさまに敵意をもって
with outrageous ease
いとも簡単に
with panache
堂々と
with perfect coolness
落ち着き払って
with pinpoint accuracy [precision]
きわめて正確に
with premeditation
故意に
with profit
ためになって
with reckless [gay, wild] abandon
あとさきを考えずに
with [in] regard to ...
…に関して(は)